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Cyclophilin A (CypA) Plays Dual Roles in Regulation of Bone Anabolism and Resorption
CypA (Cyclophilin A) is a peptidyl-prolyl isomerase previously shown to be required for chondrogenic differentiation and endochondral ossification. However, the effects of CypA on osteoclast activity and bone maintenance are entirely unknown. Here, we show that Ppia(−/−) mice demonstrate low bone mi...
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| Publicado no: | Sci Rep |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4774113/ https://ncbi.nlm.nih.gov/pubmed/26932182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22378 |
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