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Cyclophilin A (CypA) Plays Dual Roles in Regulation of Bone Anabolism and Resorption

CypA (Cyclophilin A) is a peptidyl-prolyl isomerase previously shown to be required for chondrogenic differentiation and endochondral ossification. However, the effects of CypA on osteoclast activity and bone maintenance are entirely unknown. Here, we show that Ppia(−/−) mice demonstrate low bone mi...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Guo, Mian, James, Aaron W., Kwak, Jin Hee, Shen, Jia, Yokoyama, Kazunari K., Ting, Kang, Soo, Chia B., Chiu, Robert H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774113/
https://ncbi.nlm.nih.gov/pubmed/26932182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22378
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