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Involvement of the TetR-Type Regulator PaaR in the Regulation of Pristinamycin I Biosynthesis through an Effect on Precursor Supply in Streptomyces pristinaespiralis

Pristinamycin I (PI), produced by Streptomyces pristinaespiralis, is a streptogramin type B antibiotic, which contains two proteinogenic and five aproteinogenic amino acid precursors. PI is coproduced with pristinamycin II (PII), a member of streptogramin type A antibiotics. The PI biosynthetic gene...

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Dettagli Bibliografici
Pubblicato in:J Bacteriol
Autori principali: Zhao, Yawei, Feng, Rongrong, Zheng, Guosong, Tian, Jinzhong, Ruan, Lijun, Ge, Mei, Jiang, Weihong, Lu, Yinhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438209/
https://ncbi.nlm.nih.gov/pubmed/25868645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00045-15
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