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Functions that Protect Escherichia coli from Tightly Bound DNA-Protein Complexes Created by Mutant EcoRII Methyltransferase

Expression of mutant EcoRII methyltransferase protein (M.EcoRII-C186A) in Escherichia coli leads to tightly bound DNA-protein complexes (TBCs), located sporadically on the chromosome rather than in tandem arrays. The mechanisms behind the lethality induced by such sporadic TBCs are not well studied,...

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Bibliographic Details
Published in:PLoS One
Main Authors: Henderson, Morgan L., Kreuzer, Kenneth N
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437897/
https://ncbi.nlm.nih.gov/pubmed/25993347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128092
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