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Regulation of EcoRII methyltransferase: effect of mutations on gene expression and in vitro binding to the promoter region.

EcoRII Methyltransferase (M.EcoRII) which methylates the second C in the sequence CCWGG (W = A/T) is autogenously regulated by binding to the 5' regulatory region of its gene. DNase I footprinting experiments demonstrated that purified M.EcoRII protected a 47-49 bp region of DNA immediately ups...

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Main Authors: Som, S, Friedman, S
格式: Artigo
語言:Inglês
出版: 1994
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC332081/
https://ncbi.nlm.nih.gov/pubmed/7816624
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