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Efficient Human Immunodeficiency Virus (HIV-1) Infection of Cells Lacking PDZD8

PDZD8 can bind the capsid proteins of different retroviruses, and transient knockdown of PDZD8 results in a decrease in the efficiency of an early, post-entry event in the retrovirus life cycle. Here we used the CRISPR-CAS9 system to create cell lines in which PDZD8 expression is stably eliminated....

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Zhang, Shijian, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437853/
https://ncbi.nlm.nih.gov/pubmed/25771112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.01.034
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