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Fasudil and SOD Packaged in Peptide-studded-liposomes: Properties, Pharmacokinetics and Ex-vivo Targeting to Isolated Perfused Rat Lungs

The present study investigated the feasibility of encapsulating two drugs, fasudil and superoxide dismutase (SOD), into liposomes for targeted and inhalational delivery to the pulmonary vasculature to treat pulmonary arterial hypertension (PAH). Nanosized liposomes were prepared by a thin-film forma...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Gupta, Nilesh, Al-Saikhan, Fahad I, Patel, Brijeshkumar, Rashid, Jahidur, Ahsan, Fakhrul
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437816/
https://ncbi.nlm.nih.gov/pubmed/25888802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2015.04.031
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