Natural Killer Cells Promote Long-Term Hepatobiliary Inflammation in a Low-Dose Rotavirus Model of Experimental Biliary Atresia

Biliary atresia is a rapidly progressive obstructive cholangiopathy of infants. Mechanistic studies in the mouse model of Rhesus rotavirus (RRV)-induced biliary atresia have linked the importance of effector lymphocytes to the pathogenesis of extrahepatic bile duct (EHBD) injury and obstruction in e...

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Bibliographic Details
Published in:PLoS One
Main Authors: Squires, James E., Shivakumar, Pranavkumar, Mourya, Reena, Bessho, Kazuhiko, Walters, Stephanie, Bezerra, Jorge A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437784/
https://ncbi.nlm.nih.gov/pubmed/25992581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127191
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