NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade

BACKGROUND: Melanoma is one of the few types of cancer with an increasing annual incidence. While a number of immunotherapies for melanoma have been associated with significant clinical benefit, including high-dose IL-2 and cytotoxic T lymphocyte antigen 4 (CTLA-4) blockade, clinical response to eit...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Immunother Cancer
Huvudupphovsmän: Kohlhapp, Frederick J, Broucek, Joseph R, Hughes, Tasha, Huelsmann, Erica J, Lusciks, Jevgenijs, Zayas, Janet P, Dolubizno, Hubert, Fleetwood, Vidyaratna A, Grin, Alisa, Hill, Graham E, Poshepny, Joseph L, Nabatiyan, Arman, Ruby, Carl E, Snook, Joshua D, Rudra, Jai S, Schenkel, Jason M, Masopust, David, Zloza, Andrew, Kaufman, Howard L
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437746/
https://ncbi.nlm.nih.gov/pubmed/25992289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-015-0063-3
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk