NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade

BACKGROUND: Melanoma is one of the few types of cancer with an increasing annual incidence. While a number of immunotherapies for melanoma have been associated with significant clinical benefit, including high-dose IL-2 and cytotoxic T lymphocyte antigen 4 (CTLA-4) blockade, clinical response to eit...

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Detaylı Bibliyografya
Yayımlandı:J Immunother Cancer
Asıl Yazarlar: Kohlhapp, Frederick J, Broucek, Joseph R, Hughes, Tasha, Huelsmann, Erica J, Lusciks, Jevgenijs, Zayas, Janet P, Dolubizno, Hubert, Fleetwood, Vidyaratna A, Grin, Alisa, Hill, Graham E, Poshepny, Joseph L, Nabatiyan, Arman, Ruby, Carl E, Snook, Joshua D, Rudra, Jai S, Schenkel, Jason M, Masopust, David, Zloza, Andrew, Kaufman, Howard L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437746/
https://ncbi.nlm.nih.gov/pubmed/25992289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-015-0063-3
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