MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation

BACKGROUND: Lung adenocarcinoma patients with EGFR gene mutations have shown a dramatic response to gefitinib. However, drug resistance eventually emerges which limits the mean duration of response. With that in view, we examined the correlations between MET gene status as assessed by fluorescence i...

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Publicado en:BMC Cancer
Main Authors: Noro, Rintaro, Seike, Masahiro, Zou, Fenfei, Soeno, Chie, Matsuda, Kuniko, Sugano, Teppei, Nishijima, Nobuhiko, Matsumoto, Masaru, Kitamura, Kazuhiro, Kosaihira, Seiji, Minegishi, Yuji, Yoshimura, Akinobu, Kubota, Kaoru, Gemma, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437672/
https://ncbi.nlm.nih.gov/pubmed/25886066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1019-1
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