MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation

BACKGROUND: Lung adenocarcinoma patients with EGFR gene mutations have shown a dramatic response to gefitinib. However, drug resistance eventually emerges which limits the mean duration of response. With that in view, we examined the correlations between MET gene status as assessed by fluorescence i...

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Gepubliceerd in:BMC Cancer
Hoofdauteurs: Noro, Rintaro, Seike, Masahiro, Zou, Fenfei, Soeno, Chie, Matsuda, Kuniko, Sugano, Teppei, Nishijima, Nobuhiko, Matsumoto, Masaru, Kitamura, Kazuhiro, Kosaihira, Seiji, Minegishi, Yuji, Yoshimura, Akinobu, Kubota, Kaoru, Gemma, Akihiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437672/
https://ncbi.nlm.nih.gov/pubmed/25886066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1019-1
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