MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation

BACKGROUND: Lung adenocarcinoma patients with EGFR gene mutations have shown a dramatic response to gefitinib. However, drug resistance eventually emerges which limits the mean duration of response. With that in view, we examined the correlations between MET gene status as assessed by fluorescence i...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Noro, Rintaro, Seike, Masahiro, Zou, Fenfei, Soeno, Chie, Matsuda, Kuniko, Sugano, Teppei, Nishijima, Nobuhiko, Matsumoto, Masaru, Kitamura, Kazuhiro, Kosaihira, Seiji, Minegishi, Yuji, Yoshimura, Akinobu, Kubota, Kaoru, Gemma, Akihiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437672/
https://ncbi.nlm.nih.gov/pubmed/25886066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1019-1
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