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The ATP-binding cassette transporter-2 (ABCA2) regulates esterification of plasma membrane cholesterol by modulation of sphingolipid metabolism

The ATP-binding cassette transporters are a large family (~ 48 genes divided into seven families A–G) of proteins that utilize the energy of ATP-hydrolysis to pump substrates across lipid bilayers against a concentration gradient. The ABC “A” subfamily is comprised of 13 members and transport sterol...

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Détails bibliographiques
Publié dans:Biochim Biophys Acta
Auteur principal: Davis, Warren
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437569/
https://ncbi.nlm.nih.gov/pubmed/24201375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2013.10.019
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