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Trichomonas vaginalis Flavin Reductase 1 and its Role in Metronidazole Resistance

The enzyme flavin reductase 1 (FR1) from Trichomonas vaginalis, formerly known as NADPH oxidase, was isolated and identified. Flavin reductase is part of the antioxidative defense in T. vaginalis and indirectly reduces molecular oxygen to hydrogen peroxide via free flavins. Importantly, a reduced or...

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Bibliografiske detaljer
Udgivet i:Mol Microbiol
Main Authors: Leitsch, David, Janssen, Brian D., Kolarich, Daniel, Johnson, Patricia J., Duchêne, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437529/
https://ncbi.nlm.nih.gov/pubmed/24256032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12455
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