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Down-regulation of flavin reductase and alcohol dehydrogenase-1 (ADH1) in metronidazole-resistant isolates of Trichomonas vaginalis

The microaerophilic parasite Trichomonas vaginalis is a causative agent of painful vaginitis or urethritis, termed trichomoniasis, and can also cause preterm delivery or stillbirth. Treatment of trichomoniasis is almost exclusively based on the nitroimidazole drugs metronidazole and tinidazole. Metr...

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Bibliographische Detailangaben
Hauptverfasser: Leitsch, David, Drinić, Mirjana, Kolarich, Daniel, Duchêne, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier/North-Holland Biomedical Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341570/
https://ncbi.nlm.nih.gov/pubmed/22449940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2012.03.003
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