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SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain
Glial cells can be in vivo reprogrammed into functional neurons in the adult CNS; however, the process by which this reprogramming occurs is unclear. Here, we show that a distinct cellular sequence is involved in SOX2-driven in situ conversion of adult astrocytes to neurons. This includes ASCL1(+) n...
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| Izdano u: | Stem Cell Reports |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4437485/ https://ncbi.nlm.nih.gov/pubmed/25921813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.03.006 |
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