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PSA-NCAM-Negative Neural Crest Cells Emerging during Neural Induction of Pluripotent Stem Cells Cause Mesodermal Tumors and Unwanted Grafts

Tumorigenic potential of human pluripotent stem cells (hPSCs) is an important issue in clinical applications. Despite many efforts, PSC-derived neural precursor cells (NPCs) have repeatedly induced tumors in animal models even though pluripotent cells were not detected. We found that polysialic acid...

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Detaylı Bibliyografya
Yayımlandı:Stem Cell Reports
Asıl Yazarlar: Lee, Dongjin R., Yoo, Jeong-Eun, Lee, Jae Souk, Park, Sanghyun, Lee, Junwon, Park, Chul-Yong, Ji, Eunhyun, Kim, Han-Soo, Hwang, Dong-Youn, Kim, Dae-Sung, Kim, Dong-Wook
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437469/
https://ncbi.nlm.nih.gov/pubmed/25937368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.04.002
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