PSA-NCAM-Negative Neural Crest Cells Emerging during Neural Induction of Pluripotent Stem Cells Cause Mesodermal Tumors and Unwanted Grafts

Tumorigenic potential of human pluripotent stem cells (hPSCs) is an important issue in clinical applications. Despite many efforts, PSC-derived neural precursor cells (NPCs) have repeatedly induced tumors in animal models even though pluripotent cells were not detected. We found that polysialic acid...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Reports
Auteurs principaux: Lee, Dongjin R., Yoo, Jeong-Eun, Lee, Jae Souk, Park, Sanghyun, Lee, Junwon, Park, Chul-Yong, Ji, Eunhyun, Kim, Han-Soo, Hwang, Dong-Youn, Kim, Dae-Sung, Kim, Dong-Wook
Format: Artigo
Langue:Inglês
Publié: Elsevier 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437469/
https://ncbi.nlm.nih.gov/pubmed/25937368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.04.002
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires