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Polypeptide transfer from Hsp40 to Hsp70 molecular chaperones

Heat shock protein 40 (Hsp40) co-chaperones assist in cellular protein folding and degradation through the binding and delivery of non-native proteins to heat shock protein 70 (Hsp70). The mechanism for substrate transfer from Hsp40s to Hsp70 is unknown. Two recent studies provide new details that s...

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Bibliographic Details
Published in:Trends Biochem Sci
Main Authors: Summers, Daniel W., Douglas, Peter M., Ramos, Carlos H.I., Cyr, Douglas M.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437460/
https://ncbi.nlm.nih.gov/pubmed/19359181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2008.12.009
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