A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) gene and systemic sclerosis

INTRODUCTION: The multifunctional nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) has potent anti-fibrotic effects, and its expression and activity are impaired in patients with systemic sclerosis (SSc). We investigated PPAR-γ gene (PPARG) single nucleotide polymorphisms (...

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Publicado no:Arthritis Res Ther
Principais autores: Marangoni, Roberta Goncalves, Korman, Benjamin D, Allanore, Yannick, Dieude, Philippe, Armstrong, Loren L, Rzhetskaya, Margarita, Hinchcliff, Monique, Carns, Mary, Podlusky, Sofia, Shah, Sanjiv J, Ruiz, Barbara, Hachulla, Eric, Tiev, Kiet, Cracowski, Jean-Luc, Varga, John, Hayes, M Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437446/
https://ncbi.nlm.nih.gov/pubmed/25986483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0641-2
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