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Bacterial recognition pathways that lead to inflammasome activation

Inflammasomes are multi-protein signaling platforms that upon activation trigger the maturation of the pro-inflammatory cytokines, interleukin-1β (IL-1β) and IL-18, and cell death. Inflammasome sensors detect microbial and host-derived molecules. Here, we review the mechanisms of inflammasome activa...

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Dades bibliogràfiques
Publicat a:Immunol Rev
Autors principals: Storek, Kelly M, Monack, Denise M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437016/
https://ncbi.nlm.nih.gov/pubmed/25879288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12289
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