Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair

Fibroblast growth factors (Fgfs) mediate organ repair. Lung epithelial cell overexpression of Fgf10 postbleomycin injury is both protective and therapeutic, characterized by increased survival and attenuated fibrosis. Exogenous administration of FGF7 (palifermin) also showed prophylactic survival be...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: MacKenzie, BreAnne, Henneke, Ingrid, Hezel, Stefanie, Al Alam, Denise, El Agha, Elie, Chao, Cho-Ming, Quantius, Jennifer, Wilhelm, Jochen, Jones, Matthew, Goth, Kerstin, Li, Xiaokun, Seeger, Werner, Königshoff, Melanie, Herold, Susanne, Rizvanov, Albert A., Günther, Andreas, Bellusci, Saverio
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437006/
https://ncbi.nlm.nih.gov/pubmed/25820524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00291.2014
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