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Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair

Fibroblast growth factors (Fgfs) mediate organ repair. Lung epithelial cell overexpression of Fgf10 postbleomycin injury is both protective and therapeutic, characterized by increased survival and attenuated fibrosis. Exogenous administration of FGF7 (palifermin) also showed prophylactic survival be...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Lung Cell Mol Physiol
Egile Nagusiak: MacKenzie, BreAnne, Henneke, Ingrid, Hezel, Stefanie, Al Alam, Denise, El Agha, Elie, Chao, Cho-Ming, Quantius, Jennifer, Wilhelm, Jochen, Jones, Matthew, Goth, Kerstin, Li, Xiaokun, Seeger, Werner, Königshoff, Melanie, Herold, Susanne, Rizvanov, Albert A., Günther, Andreas, Bellusci, Saverio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437006/
https://ncbi.nlm.nih.gov/pubmed/25820524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00291.2014
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