Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice

Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme mediating triacylglycerol hydrolysis in virtually all cells, including adipocytes and skeletal myocytes, and hence, plays a critical role in mobilizing fatty acids. Global ATGL deficiency promotes skeletal myopathy and exercise intoleran...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Dubé, John J., Sitnick, Mitch T., Schoiswohl, Gabriele, Wills, Rachel C., Basantani, Mahesh K., Cai, Lingzhi, Pulinilkunnil, Thomas, Kershaw, Erin E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436997/
https://ncbi.nlm.nih.gov/pubmed/25783895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00530.2014
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