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Chronic hyperleptinemia results in the development of hypertension in pregnant rats

Despite the fact that obesity is a major risk factor for preeclampsia (PE), the pathophysiological mechanisms whereby obesity and metabolic factors such as leptin increase this risk are unclear. While human data have shown that hyperleptinemia is associated with PE, the long-term effect of hyperlept...

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Опубликовано в: :Am J Physiol Regul Integr Comp Physiol
Главные авторы: Palei, Ana C., Spradley, Frank T., Granger, Joey P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436978/
https://ncbi.nlm.nih.gov/pubmed/25761697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00286.2014
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