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Differential body weight, blood pressure and placental inflammatory responses to normal versus high-fat diet in melanocortin-4 receptor-deficient pregnant rats

OBJECTIVES: Although obesity increases the risk for hypertensive disorders of pregnancy, the mechanisms remain unclear. Neural melanocortin-4 receptor (MC4R) deficiency causes hyperphagia and obesity. Effects of MC4R deficiency on body weight, blood pressure (BP) and placental inflammatory responses...

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Pubblicato in:J Hypertens
Autori principali: Spradley, Frank T., Palei, Ana C., Granger, Joey P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310251/
https://ncbi.nlm.nih.gov/pubmed/27467764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000001059
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