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Optimally choosing PWM motif databases and sequence scanning approaches based on ChIP-seq data

BACKGROUND: For many years now, binding preferences of Transcription Factors have been described by so called motifs, usually mathematically defined by position weight matrices or similar models, for the purpose of predicting potential binding sites. However, despite the availability of thousands of...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Dabrowski, Michal, Dojer, Norbert, Krystkowiak, Izabella, Kaminska, Bozena, Wilczynski, Bartek
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436866/
https://ncbi.nlm.nih.gov/pubmed/25927199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0573-5
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