Intensity of natural selection at the major histocompatibility complex loci.
Long persistence of allelic lineages, prevalence of nonsynonymous over synonymous substitutions in the peptide-binding region (PBR), and deviation from neutrality of the expected gene identity parameter F all indicate indirectly that balancing selection is operating at functional major histocompatib...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041766/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.7184 |
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