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Intensity of natural selection at the major histocompatibility complex loci.

Long persistence of allelic lineages, prevalence of nonsynonymous over synonymous substitutions in the peptide-binding region (PBR), and deviation from neutrality of the expected gene identity parameter F all indicate indirectly that balancing selection is operating at functional major histocompatib...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Satta, Y, O'hUigin, C, Takahata, N, Klein, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44363/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041766/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.7184
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