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Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation.

The prolactin (PRL) receptor is a member of the family of cytokine receptors that lack intrinsic tyrosine kinase activity but contain two conserved cysteines in their N-terminal regions and a WSXWS motif adjacent to their transmembrane domains. In a manner similar to the interferons (IFNs), exposure...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: David, M, Petricoin, E F, Igarashi, K, Feldman, G M, Finbloom, D S, Larner, A C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.7174
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