Biomarkers and cognitive endpoints to optimize trials in Alzheimer's disease

OBJECTIVE: To find the combination of candidate biomarkers and cognitive endpoints to maximize statistical power and minimize cost of clinical trials of healthy elders at risk for cognitive decline due to Alzheimer's disease. METHODS: Four-hundred and twelve cognitively normal participants were...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Insel, Philip S, Mattsson, Niklas, Mackin, R Scott, Kornak, John, Nosheny, Rachel, Tosun-Turgut, Duygu, Donohue, Michael C, Aisen, Paul S, Weiner, Michael W
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435707/
https://ncbi.nlm.nih.gov/pubmed/26000325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.192
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