Biomarkers and cognitive endpoints to optimize trials in Alzheimer's disease

OBJECTIVE: To find the combination of candidate biomarkers and cognitive endpoints to maximize statistical power and minimize cost of clinical trials of healthy elders at risk for cognitive decline due to Alzheimer's disease. METHODS: Four-hundred and twelve cognitively normal participants were...

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Vydáno v:Ann Clin Transl Neurol
Hlavní autoři: Insel, Philip S, Mattsson, Niklas, Mackin, R Scott, Kornak, John, Nosheny, Rachel, Tosun-Turgut, Duygu, Donohue, Michael C, Aisen, Paul S, Weiner, Michael W
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435707/
https://ncbi.nlm.nih.gov/pubmed/26000325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.192
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