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Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis

Deregulated expression of heat shock proteins (HSPs) encoding genes is frequent in multiple myeloma. HSPs, which are molecular chaperones involved in protein homeostasis pathways, have emerged recently as promising therapeutic targets. Using human myeloma cell lines and primary myeloma cells belongi...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Bustany, Sophie, Cahu, Julie, Descamps, Géraldine, Pellat-Deceunynck, Catherine, Sola, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435646/
https://ncbi.nlm.nih.gov/pubmed/25898974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0135-3
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