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Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis

Deregulated expression of heat shock proteins (HSPs) encoding genes is frequent in multiple myeloma. HSPs, which are molecular chaperones involved in protein homeostasis pathways, have emerged recently as promising therapeutic targets. Using human myeloma cell lines and primary myeloma cells belongi...

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Foilsithe in:J Hematol Oncol
Main Authors: Bustany, Sophie, Cahu, Julie, Descamps, Géraldine, Pellat-Deceunynck, Catherine, Sola, Brigitte
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435646/
https://ncbi.nlm.nih.gov/pubmed/25898974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0135-3
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