Restoration of the Majority of the Visual Spectrum by Using Modified Volvox Channelrhodopsin-1

We previously showed that blind rats whose vision was restored by gene transfer of Chlamydomonas channelrhodopsin-2 (ChR2) could only detect wavelengths less than 540 nm because of the action spectrum of the transgene product. Volvox-derived channelrhodopsin-1, VChR1, has a broader spectrum than ChR...

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Detalles Bibliográficos
Publicado en:Mol Ther
Main Authors: Tomita, Hiroshi, Sugano, Eriko, Murayama, Namie, Ozaki, Taku, Nishiyama, Fumiaki, Tabata, Kitako, Takahashi, Maki, Saito, Takehiko, Tamai, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435592/
https://ncbi.nlm.nih.gov/pubmed/24821344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.81
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