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Essential Role of Thioredoxin 2 in Mitigating Oxidative Stress in Retinal Epithelial Cells

The retina is constantly subjected to oxidative stress, which is countered by potent antioxidative systems present in retinal pigment epithelial (RPE) cells. Disruption of these systems leads to the development of age-related macular degeneration. Thioredoxin 2 (Trx2) is a potent antioxidant, which...

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Autors principals: Sugano, Eriko, Murayama, Namie, Takahashi, Maki, Tabata, Kitako, Tamai, Makoto, Tomita, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844160/
https://ncbi.nlm.nih.gov/pubmed/24319591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/185825
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