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A novel 4-base-recognizing RNA cutter that can remove the single 3′ terminal nucleotides from RNA molecules
Mammalian tRNase ZL shows versatility in substrate recognition. This enzyme can not only process pre-tRNAs by cleaving off their 3′ trailer sequences, but also recognize and cleave pre-tRNA-like complexes and micro-pre-tRNAs. Here we demonstrate that 24–27 nt hairpin RNAs (hook RNAs) can guide cleav...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC443559/ https://ncbi.nlm.nih.gov/pubmed/15247324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh092 |
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