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Identification by Mn(2+) rescue of two residues essential for the proton transfer of tRNase Z catalysis
Thermotoga maritima tRNase Z cleaves pre-tRNAs containing the (74)CCA(76) sequence precisely after the A(76) residue to create the mature 3′ termini. Its crystal structure has revealed a four-layer αβ/βα sandwich fold that is typically found in the metallo-β-lactamase superfamily. The well-conserved...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1540738/ https://ncbi.nlm.nih.gov/pubmed/16916792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl517 |
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