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Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy

The development of robust nonviral vectors could facilitate clinical gene therapy applications and may overcome some of the immune complications of viral vectors. Nevertheless, most nonviral gene deliver approaches typically yield only transient and/or low gene expression. To address these caveats,...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Di Matteo, Mario, Samara-Kuko, Emira, Ward, Natalie J, Waddingon, Simon N, McVey, John H, Chuah, Marinee KL, VandenDriessche, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435487/
https://ncbi.nlm.nih.gov/pubmed/25034357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.131
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