Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy

The development of robust nonviral vectors could facilitate clinical gene therapy applications and may overcome some of the immune complications of viral vectors. Nevertheless, most nonviral gene deliver approaches typically yield only transient and/or low gene expression. To address these caveats,...

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Publicat a:Mol Ther
Autors principals: Di Matteo, Mario, Samara-Kuko, Emira, Ward, Natalie J, Waddingon, Simon N, McVey, John H, Chuah, Marinee KL, VandenDriessche, Thierry
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435487/
https://ncbi.nlm.nih.gov/pubmed/25034357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.131
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