Regulation of the large (∼1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn

Most cases of Angelman syndrome (AS) result from loss or inactivation of ubiquitin protein ligase 3A (UBE3A), a gene displaying maternal-specific expression in brain. Epigenetic silencing of the paternal UBE3A allele in brain appears to be mediated by a non-coding UBE3A antisense (UBE3A-ATS). In hum...

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Main Authors: Landers, Miguel, Bancescu, Daria L., Le Meur, Elodie, Rougeulle, Claire, Glatt-Deeley, Heather, Brannan, Camilynn, Muscatelli, Françoise, Lalande, Marc
格式: Artigo
語言:Inglês
出版: Oxford University Press 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC443545/
https://ncbi.nlm.nih.gov/pubmed/15226413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh670
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