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Influence of in vitro manipulation on the stability of methylation patterns in the Snurf/Snrpn-imprinting region in mouse embryonic stem cells
Recent work on embryonic stem (ES) cells showed that stem cell-derived tissues and embryos, cloned from ES cell nuclei, often fail to maintain epigenetic states of imprinted genes. This deregulation is frequently associated with in vitro manipulations and culture conditions which might affect the ce...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2004
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390307/ https://ncbi.nlm.nih.gov/pubmed/15004243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh322 |
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