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SRY Induced TCF21 Genome-Wide Targets and Cascade of bHLH Factors During Sertoli Cell Differentiation and Male Sex Determination in Rats

Male sex determination is initiated through the testis-determining factor SRY that promotes Sertoli cell differentiation and subsequent gonadal development. The basic helix-loop-helix (bHLH) gene Tcf21 was identified as one of the direct downstream targets of SRY. The current study was designed to i...

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Pubblicato in:Biol Reprod
Autori principali: Bhandari, Ramji K., Schinke, Ellyn N., Haque, Md. M., Sadler-Riggleman, Ingrid, Skinner, Michael K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for the Study of Reproduction, Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435424/
https://ncbi.nlm.nih.gov/pubmed/23034159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.099663
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