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SRY Induced TCF21 Genome-Wide Targets and Cascade of bHLH Factors During Sertoli Cell Differentiation and Male Sex Determination in Rats

Male sex determination is initiated through the testis-determining factor SRY that promotes Sertoli cell differentiation and subsequent gonadal development. The basic helix-loop-helix (bHLH) gene Tcf21 was identified as one of the direct downstream targets of SRY. The current study was designed to i...

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Détails bibliographiques
Publié dans:Biol Reprod
Auteurs principaux: Bhandari, Ramji K., Schinke, Ellyn N., Haque, Md. M., Sadler-Riggleman, Ingrid, Skinner, Michael K.
Format: Artigo
Langue:Inglês
Publié: Society for the Study of Reproduction, Inc. 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435424/
https://ncbi.nlm.nih.gov/pubmed/23034159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.099663
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