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Interactions of the KWK(6) cationic peptide with short nucleic acid oligomers: demonstration of large Coulombic end effects on binding at 0.1–0.2 M salt
We quantify Coulombic end effects (CEE) on oligocation–nucleic acid interactions at salt concentrations ([salt]) in the physiological range. Binding constants (K(obs); per site, at zero binding density) for the +8-charged C-amidated oligopeptide KWK(6) and short single-stranded DNA oligonucleotides...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC443526/ https://ncbi.nlm.nih.gov/pubmed/15205469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh646 |
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