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Impact of Obesity on Ovotoxicity Induced by 7,12-dimethylbenz[a]anthracene in Mice

Insulin, elevated during obesity, regulates xenobiotic biotransformation enzymes, potentially through phosphatidylinositol 3-kinase (PI3K) signaling, in extraovarian tissues. PI3K regulates oocyte viability, follicular activation, and ovarian chemical biotransformation. 7,12-Dimethylbenz[a]anthracen...

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Bibliografski detalji
Izdano u:Biol Reprod
Glavni autori: Nteeba, Jackson, Ganesan, Shanthi, Keating, Aileen F.
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435232/
https://ncbi.nlm.nih.gov/pubmed/24501177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.114215
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