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Impact of Obesity on Ovotoxicity Induced by 7,12-dimethylbenz[a]anthracene in Mice
Insulin, elevated during obesity, regulates xenobiotic biotransformation enzymes, potentially through phosphatidylinositol 3-kinase (PI3K) signaling, in extraovarian tissues. PI3K regulates oocyte viability, follicular activation, and ovarian chemical biotransformation. 7,12-Dimethylbenz[a]anthracen...
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| Publicado no: | Biol Reprod |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for the Study of Reproduction, Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4435232/ https://ncbi.nlm.nih.gov/pubmed/24501177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.114215 |
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