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Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27

Polycomb group (PcG) complexes 2 and 3 are involved in transcriptional silencing. These complexes contain a histone lysine methyltransferase (HKMT) activity that targets different lysine residues on histones H1 or H3 in vitro. However, it is not known if these histones are methylation targets in viv...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kirmizis, Antonis, Bartley, Stephanie M., Kuzmichev, Andrei, Margueron, Raphael, Reinberg, Danny, Green, Roland, Farnham, Peggy J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC443521/
https://ncbi.nlm.nih.gov/pubmed/15231737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1200204
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