Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27

Polycomb group (PcG) complexes 2 and 3 are involved in transcriptional silencing. These complexes contain a histone lysine methyltransferase (HKMT) activity that targets different lysine residues on histones H1 or H3 in vitro. However, it is not known if these histones are methylation targets in viv...

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Main Authors: Kirmizis, Antonis, Bartley, Stephanie M., Kuzmichev, Andrei, Margueron, Raphael, Reinberg, Danny, Green, Roland, Farnham, Peggy J.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2004
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Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC443521/
https://ncbi.nlm.nih.gov/pubmed/15231737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1200204
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