Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes

BACKGROUND: The agouti protein is a paracrine factor that is normally present in the skin of many species of mammals. Agouti regulates the switch between black and yellow hair pigmentation by signalling through the melanocortin 1 receptor (Mc1r) on melanocytes. Lethal yellow (A(y)) and viable yellow...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kuklin, Alexander I, Mynatt, Randall L, Klebig, Mitchell L, Kiefer, Laura L, Wilkison, William O, Woychik, Richard P, Michaud, Edward J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC443512/
https://ncbi.nlm.nih.gov/pubmed/15175105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-17
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados