Common Oncogene Mutations and Novel SND1-BRAF Transcript Fusion in Lung Adenocarcinoma from Never Smokers

Lung adenocarcinomas from never smokers account for approximately 15 to 20% of all lung cancers and these tumors often carry genetic alterations that are responsive to targeted therapy. Here we examined mutation status in 10 oncogenes among 89 lung adenocarcinomas from never smokers. We also screene...

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Publicat a:Sci Rep
Autors principals: Jang, Jin Sung, Lee, Adam, Li, Jun, Liyanage, Hema, Yang, Yanan, Guo, Lixia, Asmann, Yan W., Li, Peter W., Erickson-Johnson, Michele, Sakai, Yuta, Sun, ZhiFu, Jeon, Hyo-Sung, Hwang, Hayoung, Bungum, Aaron O., Edell, Eric S., Simon, Vernadette A., Kopp, Karla J., Eckloff, Bruce, Oliveira, Andre M., Wieben, Eric, Aubry, Marie Christine, Yi, Eunhee, Wigle, Dennis, Diasio, Robert B., Yang, Ping, Jen, Jin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434945/
https://ncbi.nlm.nih.gov/pubmed/25985019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09755
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