Viral Transduction of Male Germline Stem Cells Results in Transgene Transmission after Germ Cell Transplantation in Pigs

Genetic modification of germline stem cells (GSCs) is an alternative approach to generate large transgenic animals where transgenic GSCs are transplanted into a recipient testis to generate donor-derived transgenic sperm. The objective of the present study was to explore the application of viral vec...

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Vydáno v:Biol Reprod
Hlavní autoři: Zeng, Wenxian, Tang, Lin, Bondareva, Alla, Honaramooz, Ali, Tanco, Valeria, Dores, Camila, Megee, Susan, Modelski, Mark, Rodriguez-Sosa, Jose Rafael, Paczkowski, Melissa, Silva, Elena, Wheeler, Matt, Krisher, Rebecca L., Dobrinski, Ina
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for the Study of Reproduction, Inc. 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434942/
https://ncbi.nlm.nih.gov/pubmed/23221397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.104422
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