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The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains

The Smc5-6 complex is required for the maintenance of genome integrity through its functions in DNA repair and chromosome biogenesis. However, the specific mode of action of Smc5 and Smc6 in these processes remains largely unknown. We previously showed that individual components of the Smc5-Smc6 com...

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Publicado en:Sci Rep
Main Authors: Roy, Marc-André, Dhanaraman, Thillaivillalan, D’Amours, Damien
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434891/
https://ncbi.nlm.nih.gov/pubmed/25984708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09797
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